152876-70-5Relevant articles and documents
Microwave-Assisted Nickel-Catalyzed Synthesis of Benzimidazoles: Ammonia as a Cheap and Nontoxic Nitrogen Source
Ke, Fang,Zhang, Peng,Xu, Yiwen,Lin, Xiaoyan,Lin, Jin,Lin, Chen,Xu, Jianhua
, p. 2722 - 2726 (2018)
An efficient and convenient Ni-catalyzed C-N bond formation for the synthesis of various benzimidazoles from various 2-haloanilines, aldehydes, and ammonia in a concise manner is reported. This protocol uses commercially available, nonhazardous, clean ammonia as a reaction partner instead of other nitrogen sources. Benzimidazoles, as the sole products, were obtained in high to excellent yields (up to 95%).
