152898-20-9

Basic information

• Product Name: 17-benzyloxy-19-methylbenzo-1,4,7,10,13,16-hexaoxacyclooctadecane
• CAS NO: 152898-20-9
• Molecular Weight: 432.514
• Mol File: 152898-20-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 17-benzyloxy-19-methylbenzo-1,4,7,10,13,16-hexaoxacyclooctadecane(CAS DataBase Reference)
• NIST Chemistry Reference: 17-benzyloxy-19-methylbenzo-1,4,7,10,13,16-hexaoxacyclooctadecane(152898-20-9)
• EPA Substance Registry System: 17-benzyloxy-19-methylbenzo-1,4,7,10,13,16-hexaoxacyclooctadecane(152898-20-9)

Safety Data

• Hazardous Substances Data: 152898-20-9(Hazardous Substances Data)

Upstream product

• 152898-02-7 4-benzyloxy-2-ethoxy-6-methyl-1,3-benzodioxole 
• 152898-01-6 2-ethoxy-4-hydroxy-6-methyl-1,3-benzodioxole 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 6443-69-2 3,4,5-trimethoxytoluene 
• 609-25-6 5-methylpyrogallol 
• 57602-02-5 1,14-dibromo-3,6,9,12-tetraoxatetradecane 
• 152898-03-8 3-benzyloxy-5-methyl-1,2-benzenediol 

Relevant articles and documents

Synthesis of crown ethers related to ubiquinones

Crown ethers in which the two methoxy groups of ubiquinone-0 (2,3-dimethoxy-5-methyl-1,4-benzoquinone) are replaced by oligoethylene glycol bridges have been obtained in five straightforward steps in 35-40% overall yield from 5-methylpyrogallol. A Fremy salt oxidation of a phenolic precursor is used in the final step. The further elaboration of crown ether analogues of ubiquinone-2 was achieved by enol geranylation of cyclopentadiene adducts of the former quinones and subsequent retro-Diels-Alder reaction. The Claisen rearrangement of 2,2-dimethoxy-5-methylphenyl allyl ethers and related crown ethers affords ortho- and para-allyl-substituted phenols (3:1) that are oxidized to give bisnorubiquinone derivatives and their ortho-quinone isomers. All new compounds are characterized by high resolution NMR and mass spectrometry.