152937-75-2Relevant academic research and scientific papers
Synthesis of benzo[b]carbazoloquinones by coupling of organostannanes with bromoquinones
Echavarren, Antonio M.,Tamayo, Nuria,De Frutos, Oscar,Garcia, Alicia
, p. 16835 - 16846 (2007/10/03)
The synthesis of 5-carbonitrile-1,7-dihydroxy-3-methyl-SH- benzo[b]carbazole-6,11-dione, the quinone originally proposed as prekinamycin, was completed by using a palladium and copper catalyzed Stille reaction as the key step. A subsequent heterocyclizati
Synthesis of the benzo[b] carbazoloquinone with the structure proposed for prekinamycin
Echavarren, Antonio M.,Tamayo, Nuria,Carmen Paredes
, p. 4713 - 4716 (2007/10/02)
The synthesis of the N-cyano benzo[b]carbazolequinone with the structure proposed for prekinamycin has been achieved by palladium and copper catalyzed coupling of a 2-bromonaphthoquinone with an arylstannane followed by ring closure, N-cyanation, and demethylation. Unexpectedly, the ring closure reaction gave also a regioisomer by an unprecedented rearrangement reaction.
