152955-15-2

Upstream product

• 126809-68-5 2-(methoxymethoxy)-4-methoxybenzyl alcohol 
• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 124555-63-1 4-methoxy-2-methoxymethoxy benzaldehyde 

Downstream Products

• 152955-19-6 methyl 2-phenyl-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 213970-32-2 methyl 2-(3,4-dimethoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 213970-29-7 methyl 2-(4-methoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 152955-20-9 methyl 2-(2-methoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 213970-33-3 methyl 2-(2,4-dimethoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 225089-86-1 (+)-(4S,5R)-1,5-dimethyl-4-phenyl-3-<2'-(4-methoxyphenyl)-3'-(4-methoxy-2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 225090-00-6 (-)-(4R,5S)-1,5-dimethyl-4-phenyl-3-<2'-(4-methoxyphenyl)-3'-(4-methoxy-2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 225090-02-8 (-)-(4R,5S)-1,5-dimethyl-4-phenyl-3-<2'-(2,4-dimethoxyphenyl)-3'-(4-methoxy-2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 225089-88-3 (+)-(4S,5R)-1,5-dimethyl-4-phenyl-3-<2'-(2,4-dimethoxyphenyl)-3'-(4-methoxy-2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 5093-45-8 2',7-dimethoxyisoflavan 
• 4308-55-8 7-Methoxyisoflavan 
• 152955-28-7 3-(2-hydroxy-4-methoxyphenyl)-2-phenyl-1-propanol 
• 152955-24-3 2-phenyl-3-(4-methoxy-2-O-methoxymethylphenyl)-1-propanol 
• 152955-29-8 3-(2-hydroxy-4-methoxyphenyl)-2-(2-methoxyphenyl)-1-propanol 

Relevant academic research and scientific papers

Total synthesis of unsymmetrical benzils, scandione and calophione A

The synthesis of the title unsymmetrical benzils, scandione and calophione A, is described. The key processes involve intramolecular cyclization reaction of the carbanion at the benzylic position of the arylbenzyl ether to the adjacent ester group followed by oxidation. The palladium(II)-catalyzed oxidative cyclization was also used to establish the benzofuran unit of calophione A. A convergent synthesis of the title benzils, which embody the 1,2-diarylethane-1,2-dione system, is reported. Key steps involve intramolecular cyclization of the carbanion at the benzylic position of the arylbenzyl ether to the adjacent ester group followed by oxidation. The palladium(II)-catalyzed oxidative cyclization was also studied to establish the benzofuran unit of calophione A. Copyright

BRIDGED AND FUSED ANTIDIABETIC COMPOUNDS

ABSTRACT This invention provides for certain bridged and fused compounds of the formula G-L-A I or a pharmaceutically acceptable salt, ester of solvate thereof wherein: A is: (I) and the other variables are defined herein; the inventive compounds are agon

The direct synthesis of isoflavans VIA α-alkylation of phenylacetates

Deprotonation of oxygenated phenylacetates and quenching of the enolates with oxygenated benzylic electrophiles, afforded 2,3-diarylpropanoates which served as precursors to the isoflavans following consecutive reduction and cyclization steps.

THE FIRST DIRECT SYNTHESIS OF ISOFLAVANS VIA α-ALKYLATION OF PHENYLACETATES

Deprotonation of phenylacetates and quenching of the enolates with benzylic electrophiles, afford 2,3-diarylpropanoates which serve as precursors to isoflavans following consecutive reduction and cyclization steps.