152955-15-2

Basic information

• Product Name: 4-methoxy-2-O-methoxymethylbenzyl bromide
• Synonyms: 4-methoxy-2-O-methoxymethylbenzyl bromide
• CAS NO: 152955-15-2
• Molecular Weight: 261.115
• Mol File: 152955-15-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-methoxy-2-O-methoxymethylbenzyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxy-2-O-methoxymethylbenzyl bromide(152955-15-2)
• EPA Substance Registry System: 4-methoxy-2-O-methoxymethylbenzyl bromide(152955-15-2)

Safety Data

• Hazardous Substances Data: 152955-15-2(Hazardous Substances Data)

Upstream product

• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 124555-63-1 4-methoxy-2-methoxymethoxy benzaldehyde 
• 126809-68-5 2-(methoxymethoxy)-4-methoxybenzyl alcohol 

Downstream Products

• 152955-19-6 methyl 2-phenyl-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 213970-32-2 methyl 2-(3,4-dimethoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 213970-29-7 methyl 2-(4-methoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 152955-20-9 methyl 2-(2-methoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 213970-33-3 methyl 2-(2,4-dimethoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)propanoate 
• 225089-86-1 (+)-(4S,5R)-1,5-dimethyl-4-phenyl-3-<2'-(4-methoxyphenyl)-3'-(4-methoxy-2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 225090-00-6 (-)-(4R,5S)-1,5-dimethyl-4-phenyl-3-<2'-(4-methoxyphenyl)-3'-(4-methoxy-2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 225090-02-8 (-)-(4R,5S)-1,5-dimethyl-4-phenyl-3-<2'-(2,4-dimethoxyphenyl)-3'-(4-methoxy-2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 225089-88-3 (+)-(4S,5R)-1,5-dimethyl-4-phenyl-3-<2'-(2,4-dimethoxyphenyl)-3'-(4-methoxy-2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 69651-87-2 (S)-7,2',4'-trimethoxyisoflavan 
• 225090-14-2 (S)-2-(3-hydroxy-2-(4-methoxyphenyl)propyl)-5-methoxyphenol 
• 225090-19-7 (R)-2-(3-hydroxy-2-(4-methoxyphenyl)propyl)-5-methoxyphenol 
• 225089-91-8 (S)-2-(4-methoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)-1-propanol 
• 225090-05-1 (R)-2-(4-methoxyphenyl)-3-(4-methoxy-2-O-methoxymethylphenyl)-1-propanol 

Relevant articles and documents

Total synthesis of unsymmetrical benzils, scandione and calophione A

The synthesis of the title unsymmetrical benzils, scandione and calophione A, is described. The key processes involve intramolecular cyclization reaction of the carbanion at the benzylic position of the arylbenzyl ether to the adjacent ester group followed by oxidation. The palladium(II)-catalyzed oxidative cyclization was also used to establish the benzofuran unit of calophione A. A convergent synthesis of the title benzils, which embody the 1,2-diarylethane-1,2-dione system, is reported. Key steps involve intramolecular cyclization of the carbanion at the benzylic position of the arylbenzyl ether to the adjacent ester group followed by oxidation. The palladium(II)-catalyzed oxidative cyclization was also studied to establish the benzofuran unit of calophione A. Copyright

The direct synthesis of isoflavans VIA α-alkylation of phenylacetates

Deprotonation of oxygenated phenylacetates and quenching of the enolates with oxygenated benzylic electrophiles, afforded 2,3-diarylpropanoates which served as precursors to the isoflavans following consecutive reduction and cyclization steps.