152955-44-7

Basic information

• Product Name: (2R,3R,4S)-1-(4-toluenesulfonyl)-2-(4-toluenesulfonyloxymethyl)-3-methyl-4-(4-toluenesulfonyloxy)pyrrolidine
• Synonyms: (2R,3R,4S)-1-(4-toluenesulfonyl)-2-(4-toluenesulfonyloxymethyl)-3-methyl-4-(4-toluenesulfonyloxy)pyrrolidine
• CAS NO: 152955-44-7
• Molecular Weight: 593.743
• Mol File: 152955-44-7.mol

Chemical Properties

• CAS DataBase Reference: (2R,3R,4S)-1-(4-toluenesulfonyl)-2-(4-toluenesulfonyloxymethyl)-3-methyl-4-(4-toluenesulfonyloxy)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4S)-1-(4-toluenesulfonyl)-2-(4-toluenesulfonyloxymethyl)-3-methyl-4-(4-toluenesulfonyloxy)pyrrolidine(152955-44-7)
• EPA Substance Registry System: (2R,3R,4S)-1-(4-toluenesulfonyl)-2-(4-toluenesulfonyloxymethyl)-3-methyl-4-(4-toluenesulfonyloxy)pyrrolidine(152955-44-7)

Safety Data

• Hazardous Substances Data: 152955-44-7(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 152955-42-5 ethyl (2R,3R,4S)-1-(4-tolylsulfonyl)-3-methyl-4-hydroxy-2-hydroxymethylpyrrolidine 

Downstream Products

• 153061-77-9 ethyl 7-<(1R,4R,7S)-7-methyl-5-phenylmethyl-2,5-diazabicyclo<2.2.1>heptan-2-yl>-6-fluoro-1-(1,1-dimethylethyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate 
• 153061-75-7 (1R,4R,7S)-2-(4-toluenesulfonyl)-5-phenylmethyl-7-methyl-2,5-diazabicyclo<2.2.1>heptane 

Relevant articles and documents

Synthesis, in vitro and in vivo antibacterial activity of 7-(7-methyl-2,5-diazabicyclo[2.2.1]heptane)naphthyridone derivatives as analogs of BMY 40062

The synthesis and the antimicrobial activities of chiral (1R,4R,7S)- and (1S,4S,7S)-[7-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl] analogs of BMY 40062 are reported. The new derivatives have been found to be less active in vitro but as active in vivo (im) than BMY 40062. The 1R,4R,7S substituent seems promising for the design of powerful new antibiotics.