152955-55-0

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridin-4-aMine, 1-(phenylMethyl)-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridin-4-aMine, 1-(phenylMethyl)-;1-benzyl-1H-pyrrolo[2,3-b]pyridin-4-amine
• CAS NO: 152955-55-0
• Molecular Formula: C14H13N3
• Molecular Weight: 223.27312
• Mol File: 152955-55-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 473.1±35.0 °C(Predicted)
• Appearance: /
• Density: 1.20±0.1 g/cm3(Predicted)
• PKA: 9.71±0.30(Predicted)
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridin-4-aMine, 1-(phenylMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridin-4-aMine, 1-(phenylMethyl)-(152955-55-0)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridin-4-aMine, 1-(phenylMethyl)-(152955-55-0)

Safety Data

• Hazardous Substances Data: 152955-55-0(Hazardous Substances Data)

Usage

General Description

1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-(phenylmethyl)- is a chemical compound with the molecular formula C15H13N3. It is a derivative of pyrrolopyridine and contains an amine group with a phenylmethyl substituent. 1H-Pyrrolo[2,3-b]pyridin-4-amine, 1-(phenylmethyl)- is known for its potential biological activity and is of interest for pharmaceutical research. Its structure and properties make it a suitable candidate for the development of new drugs and therapeutic agents. Further studies are needed to explore its pharmacological and medicinal potential.

Upstream product

• 55052-28-3 4-chloro-7-azaindole 
• 361370-27-6 4-azido-1H-pyrrolo[2,3-b]pyridine 
• 74420-00-1 4-amino-1H-pyrrolo<2,3-b>pyridine 
• 100-44-7 benzyl chloride 

Relevant articles and documents

Ambident Heterocyclic Reactivity: The Alkylation of Pyrrolopyridines (Azaindoles, Diazaindenes)

7-Methyl-6-azaindole, 7-acetamido-4-azaindole, the substituted 4-amino-, 2-methyl- and 6-methyl-7-azaindole, and the parent 4-, 5-, 6-, and 7-azaindole systems (as anions in dimethylformamide) were alkylated with a variety of primary alkylating agents.The relative importance of charge, product development, and steric approach control in determining the alkylation pattern (pyrrole versus pyridine ring alkylation) are discussed within a framework of variable SN2 transition state structures.Frontier orbital factors appear to be relatively insignificant.The charge distribution, orbitals and energetics of these heterocyclic systems were modelled by ab initio molecular orbital calculations (STO-3G level).Specific association, involving hydrogen bonding between adjacent groups and the alkylating agent, is important in determining the alkylation pattern in some cases.