152984-82-2Relevant academic research and scientific papers
Microbial enantioselective ester hydrolysis for the preparation of optically active 4,1-benzoxazepine-3-acetic acid derivatives as squalene synthase inhibitors
Tarui, Naoki,Nakahama, Kazuo,Nagano, Yoichi,Izawa, Motowo,Matsumoto, Kiyoharu,Kori, Masakuni,Nagata, Toshiaki,Miki, Takashi,Yukimasa, Hidefumi
, p. 59 - 65 (2002)
Microbial enantioselective ester hydrolysis for the preparation of optically active (3R,5S)-(-)-5-phenyl-4,1-benzoxazepine-3-acetic acid derivatives as potent squalene synthase inhibitors was investigated. Pseudomonas diminuta and Pseudomonas taetrolens h
4,1-benzoxazepin derivatives and their use
-
, (2008/06/13)
N-containing, condensed heterocyclic compounds and salts thereof are disclosed which are useful for inhibiting squalene synthetase and fungal growth, and which are useful for treating or preventing hyperlipidemia. Also disclosed is a method for producing
