153029-73-3

Upstream product

• 153029-62-0 9-dehydro-demycarosylplatenomycin N-oxide 
• 57449-35-1 Propionic acid (11E,13E)-(4R,5S,6S,7R,9R,16R)-6-((2S,3R,4S,5S,6R)-4-dimethylamino-3,5-dihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-5-methoxy-9,16-dimethyl-2,10-dioxo-7-(2-oxo-ethyl)-oxacyclohexadeca-11,13-dien-4-yl ester 
• 153029-71-1 9-dehydro-3''-O-methyl-4''-O-(3-methylbutyl)-3-O-propionylleucomycin V N-oxide 

Relevant academic research and scientific papers

Cladinose analogues of sixteen-membered macrolide antibiotics: I. Synthesis of 4-O-Alkyl-L-cladinose analogues via glycosylation

The synthesis and biological evaluation of sixteen-membered macrolides possessing a 4-O-alkyl-α-L-cladinosyl moiety as the neutral sugar are described. The nine novel derivatives have been synthesized by glycosylation with l-thio sugars. The most active derivative of them showed prolonged antibacterial activity in rat plasma in vitro and improved pharmacokinetics.