153034-94-7

Basic information

• Product Name: 2-Fluoro-4-iodo-5-picoline
• Synonyms: 2-Fluoro-4-iodo-5-methylpyridine;2-FLUORO-4-IODO-5-PICOLINE;6-Fluoro-4-iodo-b-picoline;2-FLUORO-4-IODO-5-PICOLINE (2-FLUORO-4-IODO-5-METHYLPYRIDINE);6-Fluoro-4-iodo-3-picoline;2-Fluoro-4-iodo-5-methylpyridine≥ 99% (GC)
• CAS NO: 153034-94-7
• Molecular Formula: C₆H₅FIN
• Molecular Weight: 237.01
• Product Categories: Fluorin-contained pyridine series;Pyridine;Heterocycle;Pyridines;Boronic Acid;Building Blocks;C6;Chemical Synthesis;Heterocyclic Building Blocks;New Products for Chemical Synthesis
• Mol File: 153034-94-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 40-45℃
• Boiling Point: 244.343 °C at 760 mmHg
• Flash Point: >110°C
• Appearance: Off-white/Solid
• Density: 1.893 g/cm³
• Vapor Pressure: 0.048mmHg at 25°C
• Refractive Index: 1.587
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• Solubility: soluble in Methanol
• PKA: -1.53±0.18(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 2-Fluoro-4-iodo-5-picoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-4-iodo-5-picoline(153034-94-7)
• EPA Substance Registry System: 2-Fluoro-4-iodo-5-picoline(153034-94-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-22
• Safety Statements: 26-36-36/39
• WGK Germany: 3
• Hazardous Substances Data: 153034-94-7(Hazardous Substances Data)

Usage

Chemical Properties

crystals

InChI:InChI=1/C6H5FIN/c1-4-3-9-6(7)2-5(4)8/h2-3H,1H3

Upstream product

• 2369-19-9 2-fluoro-5-methylpyridine 
• 153034-78-7 2-Fluoro-3-iodo-5-methylpyridine 

Downstream Products

• 777096-61-4 2-fluoro-5-methyl-4-(3-trifluoromethyl-phenyl)-pyridine 
• 777096-60-3 4-(3,5-dichloro-phenyl)-2-fluoro-5-methyl-pyridine 
• 450840-79-6 5-(bromomethyl)-4-(3-chlorophenyl)-2-pyridinecarbonitrile 
• 450837-37-3 4-(((4-(3-chlorophenyl)-6-oxo-1,6-dihydro-3-pyridinyl)methoxy)(1-methyl-1H-imidazol-5-yl)methyl)benzonitrile 
• 450837-14-6 4-(((4-(3-chlorophenyl)-6-fluoro-3-pyridinyl)methoxy)(1-methyl-1H-imidazol-5-yl)methyl)benzonitrile 
• 777096-66-9 5-methyl-6-oxo-4-(3-trifluoromethyl-phenyl)-1,6-dihydro-pyridine-2-carbonitrile 
• 777096-69-2 1,5-dimethyl-6-oxo-4-(3-trifluoromethyl-phenyl)-1,6-dihydro-pyridine-2-carbonitrile 
• 777096-68-1 4-(3,5-dichloro-phenyl)-1,5-dimethyl-6-oxo-1,6-dihydro-pyridine-2-carbonitrile 

Relevant articles and documents

HETEROARYL COMPOUNDS AS INHIBITORS OF PROGRAMMED NECROSIS PATHWAY, COMPOSITION AND METHOD USING THE SAME

The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to the programmed necrosis pathway.

HETEROCYCLIC KINASE INHIBITORS

Compounds having the formula (I) are useful for inhibiting protein kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.

Farnesyltransferase inhibitors

Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.