153036-72-7

Basic information

• Product Name: 1H-Benzimidazole-5-carbonitrile,7-methyl-2-propyl-(9CI)
• Synonyms: 1H-Benzimidazole-5-carbonitrile,7-methyl-2-propyl-(9CI)
• CAS NO: 153036-72-7
• Molecular Formula: C₁₂H₁₃N₃
• Molecular Weight: 199.25172
• Product Categories: BENZIMIDAZOLE
• Mol File: 153036-72-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Benzimidazole-5-carbonitrile,7-methyl-2-propyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole-5-carbonitrile,7-methyl-2-propyl-(9CI)(153036-72-7)
• EPA Substance Registry System: 1H-Benzimidazole-5-carbonitrile,7-methyl-2-propyl-(9CI)(153036-72-7)

Safety Data

• Hazardous Substances Data: 153036-72-7(Hazardous Substances Data)

Upstream product

• 1016696-74-4 N-butyryl-4-amino-3-methylbenzoic acid 
• 1259319-11-3 N-(4-cyano-2-methylphenyl)butyramide 
• 1259319-54-4 N-(4-cyano-2-methyl-6-nitrophenyl)butyramide 

Downstream Products

• 152628-03-0 4-methyl-2-n-propyl-1H-benzimidazole-6-carboxylic acid 
• 144701-48-4 telmisatran 
• 528560-93-2 4'-[[4-methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-yl]methyl]biphenyl-2-carboxylic acid methyl ester 
• 144702-85-2 methyl 4'-[(2-n-propyl-4-methyl-6-cyano-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylate 

Relevant articles and documents

Preparation method of telmisartan

The invention relates to a preparation method of telmisartan. According to the preparation method, 3-methyl-4-n-butylamide benzoic acid is used as a raw material, an intermediate (1) is prepared through cyaniding, nitration, reduction, ring closing and other reactions, the intermediate (1) and 4 '-bromomethyl biphenyl-2-methyl formate are subjected to condensation to generate an intermediate (2), the intermediate (2) and N-methyl o-phenylenediamine are subjected to condensation to prepare an intermediate (3), and finally the telmisartan is prepared through hydrolysis. The invention develops a new preparation method of telmisartan. The raw material 3-methyl-4-n-butyrylamide benzoic acid adopted by the method is easy to obtain and low in price; the method is mild in reaction condition, easy to operate and high in yield, the cyanation reaction avoids the use of toxic cyanide, the environmental pollution is small, and the method is suitable for industrial production.