153044-48-5Relevant academic research and scientific papers
Preparation of Sulfamates and Sulfamides Using a Selective Sulfamoylation Agent
Wang, Hai-Ming,Xiong, Chao-Dong,Chen, Xiao-Qu,Hu, Chun,Wang, Dong-Yu
, p. 2595 - 2599 (2021)
Sulfamates and sulfamides are prevalent in biological molecules, but their universal synthetic methods are limited. We herein report a sulfamoylation agent with high solubility and shelf stability. Various sulfamates and sulfamides can be synthesized directly from alcohols or amines by employing this agent with high selectivity and high yields. This protocol was also successfully used for late-stage sulfamoylation of pharmaceuticals containing a hydroxyl or amino group.
Synthesis of pseudonucleosides containing chiral sulfahydantoins as aglycone (II)
Dewynter, Georges,Aouf, Nourreddine,Regainia, Zine,Montero, Jean-Louis
, p. 993 - 1004 (2007/10/03)
A series of chiral sulfahydantoins have been synthesized by alkaline cyclization starting from N-sulfamylaminoacid methyl esters. Regioselective glycosylation of these pseudopyrimidic heterocycles was carried out with a benzyl protecting group on the N-su
SUBSTITUTED 2-ARYLCARBONYLOXYMETHYL-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF
-
, (2008/06/13)
Substituted 2-arylcarbonyloxymethyl-1,2,5-thiadiazolidin-3-one 1,1-dioxide derivatives, pharmaceutical compositions containing them and methods for the treatment of degenerative diseases utilizing them.
SERINE PROTEASE INHIBITORS
-
, (2008/06/13)
Isothiazolidin-3-one-1,1 dioxide, 3-oxo-1,2,5-thiadiazolidine-1,1,-dioxide and derivatives thereof, reduce or inhibit the activity of serine proteases. Such compounds are useful as anti-inflammatory and anti-metastatic agents.
