153076-35-8Relevant academic research and scientific papers
New routes to 1,4-benzodiazepin-2,5-diones
Akssira,Boumzebra,Kasmi,Dahdouh,Roumestant,Viallefont
, p. 9051 - 9060 (2007/10/02)
1,4-benzodiazepin-2,5-diones have been synthesized in good overall yields by two routes, the first one by cyclisation of dipeptides prepared from Boc anthranilic acid and α-amino acid methyl esters, the second one by reaction of N-carboxy α-amino acid anhydrides with Boc anthranilic acid.
New synthesis of 1,4 benzodiazepine-2,5-diones by means of HCl gas catalyst
Akssira,Boumzebra,Kasmi,Dahdouh,Roumestant,Viallefont
, p. 2265 - 2272 (2007/10/02)
A new synthesis of 1,4-benzodiazepinediones 4, particularly 1,4-dihydro1H-1,4-benzodiazepine-2,5-dione, 4c key intermediate of metabolites cyclopenin 9, cyclopenol 10, cyclopeptine 11 and dehydrocyclopeptide 12, was achieved by action of dry HCl gas in DM
