153096-74-3

Upstream product

• 201553-16-4 (S)-1-O-trityl-3,4-di-O-benzyl-1,3,4-trihydroxybutan-2-one 
• 153096-71-0 (S)-3,4-Bis-benzyloxy-1-(tert-butyl-diphenyl-silanyloxy)-butan-2-one 
• 114185-00-1 1,2-di-O-benzyl-L-threitol 
• 201553-28-8 (2R,3S)-3,4-Bis-benzyloxy-2-methyl-1-trityloxy-butan-2-ol 
• 153096-72-1 (2R,3S)-3,4-Bis-benzyloxy-1-(tert-butyl-diphenyl-silanyloxy)-2-methyl-butan-2-ol 
• 201553-19-7 (2S,3S)-3,4-Bis-benzyloxy-1-trityloxy-butan-2-ol 

Downstream Products

• 144881-15-2 (2S,3S)-3-O-caffeyl-2,3,4-trihydroxy-2-methylbutan-1,4-olide 
• 18465-71-9 (3R,4R)-3,4-dihydroxy-3-methyl-4,5-dihydro-2(3H)-furanone 

Relevant academic research and scientific papers

Diastereoselectivity in Organometallic Additions to the Carbonyl Group of Protected Erythrulose Derivatives

We have investigated a number of nucleophillic additions to L-erythrulose derivatives (4-12) bearing protective O-silyl, O-benzyl, and O-trityl groups in various relative positions. The results are discussed in the frame of chelated vs nonchelated transit

ERYTHRULOSE AS A CHIRAL PRECURSOR IN ORGANIC SYNTHESIS. TOTAL SYNTHESES OF FRONTALIN AND TWO FURTHER CHIRAL COMPOUNDS IN OPTICALLY ACTIVE FORM

From L-erythrulose derivatives as the starting materials we have performed total syntheses of some natural and non-natural compounds in optically active form.The selected target molecules were the insect pheromon frontalin, a naturally occuring lactone of

Highly diastereoselective additions of organometallic reagents to 1-O-silylated 3,4-di-O-benzyl-L-erythrulose derivatives

The diastereoselectivity of the addition of several organometallic reagents to the carbonyl group of the title compounds has been investigated. Some organomagnesium reagents display high diastereoselectivities (90-99%) and the major products are those predicted by the α-chelation model.