153141-24-3

Upstream product

• 2826-25-7 2-(4-methylbenzylidene)malononitrile 
• 153897-27-9 4-[(6R,7aR)-8,8-dimethyl-2,2-dioxidotetrahydro-3a,6-methano-2,1-benzisothiazol-1(4H)-yl]-4-oxobutan-2-one 
• 153897-28-0 (R)-2-amino-3-cyano-6-methyl-5-(N-oxobornane-10,2-sultam)-4-phenyl-4H-pyran 
• 94594-90-8 (2R)-bornane-10,2-sultam 
• 153897-33-7 (R)-2-amino-4-(p-chlorophenyl)-3-cyano-6-methyl-5-(N-oxobornane-10,2-sultam)-4H-pyran 
• 15851-89-5 (E)-p-methylcinnamoyl chloride 

Downstream Products

• 1041477-73-9 C₂₂H₃₁NO₃S 
• 1392445-72-5 C₁₃H₁₆N₂O 
• 1041477-84-2 C₁₄H₁₆O 
• 1041477-79-5 N-[3-(4-methylphenyl)heptanoyl]bornane-10,2-sultam 
• 153141-36-7 (R)-3-(Dimethyl-phenyl-silanyl)-3-p-tolyl-propionic acid 
• 153141-31-2 (R)-1-((1S,5R,7R)-10,10-Dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-3-(dimethyl-phenyl-silanyl)-3-p-tolyl-propan-1-one 

Relevant academic research and scientific papers

Diastereoselective alkyl Grignard 1,4-additions to para-substituted (2R)-N-cinnamoylbornane-10,2-sultam derivatives: Influence of N-atom pyramidalization

Several typical 13C-NMR displacements (of C=O, C(α), C(β), and Cipso), as well as conformational or energy properties (S-N-C=O dihedral angle, ΔE syn/anti; HOMO/LUMO) could be correlated with the electronic parameters of p-substitute

Development of Methods for the Synthesis of Chiral, Highly Functionalized 2-Amino-4-Aryl-4H-Pyrans

The development of new methods for the asymmetric synthesis of highly functionalized 2-amino-4-aryl-4H-pyrans is described.Two alternative synthetic routes: the 1,4-conjugate addition of chiral β-ketoesters 3 or the N-acetoacetyl sultam 11 to arylidenemal

Asymmetric Alkylation of β-Ketoesters: Synthesis and Michael Additions of a Chiral Sultam-Derived Acetoacetyl Equivalent

The synthesis and Michael reaction of the chiral acetoacetyl equivalent 1 with arylidenemalonitriles 3 is reported.