153151-50-9Relevant academic research and scientific papers
A new diorganozinc-based enantioselective access to truncated D-ribo-phytosphingosine
Ayad, Tahar,Génisson, Yves,Verdu, Alexandre,Baltas, Michel,Gorrichon, Liliane
, p. 579 - 582 (2007/10/03)
The use of a trans α,β-epoxyaldehyde as a precursor of D-ribo-phytosphingosines was studied. The highly stereoselective alkylation of the aldehyde with a diorganozinc reagent was ensured through double asymmetric induction. The regioselective opening of t
Synthesis of &β-1-Homonojirimycin and &β-1-Homomannojirimycin using the Enzyme Aldolase
Holt, Karen E.,Leeper, Finian J.,Handa, Sheetal
, p. 231 - 234 (2007/10/02)
The four stereoisomers of the four-carbon azido sugar 11 have been stereoselectively synthesised by a route involving Sharpless epoxidation and all are found to be substrates for rabbit muscle fructose 1,6-bisphosphate aldolase, giving (after treatment wi
Diastereoface differentiation in addition of lithium enolates to chiral α, β-epoxyaldehydes
Escudier, Jean-Marc,Baltas, Michel,Gorrichon, Liliane
, p. 5253 - 5266 (2007/10/02)
The aldolisation reaction of lithium ester enolates with chiral α,β-epoxyaldehydes 2a-2f has been investigated. The reaction proceeds with diastereofacial preference in favour of the anti isomer (anti: syn ≈ 4:1) and can be greatly enhanced in the case of
