153152-79-5Relevant academic research and scientific papers
β-AMINO ALCOHOL-N-OXIDES AS PRECURSORS OF CHIRAL OXAZOLIDINES: SYNTHESIS OF (R)-(-)-CRYPTOSTYLINE I
Carbonnelle, Anny-Claude,Gott, Vincent,Roussi, Georges
, p. 1763 - 1769 (2007/10/02)
The access to chiral oxazolotetrahydroquinoline by base deprotonation of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-N-oxide, allowed the synthesis of (R)-(-)-cryptostyline I.
SYNTHESES OF CHIRAL OXAZOLOTETRAHYDROISOQUINOLINE AND ITS ASYMMETRIC ALKYLATION. SYNTHESIS OF (S)-(-)- AND (R)-(+)-SALSOLIDINES
Yamato, Masatoshi,Hashigaki, Kuniko,Ishikawa, Shigetaka,Qais, Nazmul
, p. 6949 - 6950 (2007/10/02)
The isoquinolinium bromide (4), on treatment with base, underwent cyclization to give the chiral oxazolotetrahydroisoquinoline (5) with a high diastereoselectivity, which was converted to optically pure salsolidine.
