153153-54-9Relevant academic research and scientific papers
A 5′-noraristeromycin enantiomer with activity towards hepatitis B virus
Seley, Katherine L.,Schneller, Stewart W.,Korba, Brent
, p. 2095 - 2099 (1997)
(+)-5′-Noraristeromycin has selective activity against hepatitis B virus (HBV) replication in 2.2.15 cells in culture, while the (-) enantiomer was found to be inactive. A modified synthesis is presented for (+)-5′-noraristeromycin. Copyright 1997 by Marc
Antiviral enantiomeric preference for 5'-noraristeromycin
Siddiqi,Chen,Schneller
, p. 551 - 554 (2007/10/02)
In order to determine if the potent antiviral properties of (±)-5'- noraristeromycin reside in one of its enantiomers, an analysis of each enantiomer has been carried out. A five-step route to the (+)-stereoisomer is described from (+)-(1R,4S)-4-hydroxy-2
