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153172-31-7

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  • (3AR,4R,6AS)-4-([(TERT-BUTYLDIMETHYLSILYL)OXY]METHYL)-2,2-DIMETHYL-HEXAHYDRO-[1,3]DIOXOLO[4,5-C]PYRROLE

    Cas No: 153172-31-7

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153172-31-7 Usage

General Description

4H-1,3-Dioxolo4,5-cpyrrole, 4-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-, (3aR,4R,6aS)- is a complex chemical compound consisting of a 4H-1,3-dioxole ring fused to a pyrrole ring, with a 4-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl- substituent. The stereochemistry of the compound is designated as (3aR,4R,6aS)-, indicating the positions of various substituents on the molecule. 4H-1,3-Dioxolo4,5-cpyrrole, 4-(1,1-dimethylethyl)dimethylsilyloxymethyltetrahydro-2,2-dimethyl-, (3aR,4R,6aS)- likely has specific applications in organic synthesis or pharmaceutical research due to its unique structure and potential reactivity.

Check Digit Verification of cas no

The CAS Registry Mumber 153172-31-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,1,7 and 2 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 153172-31:
(8*1)+(7*5)+(6*3)+(5*1)+(4*7)+(3*2)+(2*3)+(1*1)=107
107 % 10 = 7
So 153172-31-7 is a valid CAS Registry Number.

153172-31-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-O-[(tert-butyl)dimethylsilyl]-1,4-dideoxy-1,4-imino-2,3-O-isopropylidene-D-ribitol

1.2 Other means of identification

Product number -
Other names .(1S)-5-O-tert-butyldimethylsilyl-1,4-dideoxy-1,4-imino-2,3-O-isopropylidene-D-ribitol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:153172-31-7 SDS

153172-31-7Downstream Products

153172-31-7Relevant articles and documents

ANTIVIRAL AZASUGAR-CONTAINING NUCLEOSIDES

-

, (2014/06/11)

Disclosed are compounds comprising an azasugar attached to a heterocyclic base, including pharmaceutically acceptable salts thereof, suitable for use in inhibiting viral RNA polymerase activity or viral replication, and treating viral infections. The compounds are characterized, in part, by favorable pharmacokinetics for the active pharmaceutical ingredient, particularly in conjunction with enteral administration, including, in particular, oral administration. Also disclosed are pharmaceutical compositions comprising one or more compounds mentioned above, or pharmaceutically acceptable salts thereof, as well as methods for preparing same. Also provided are methods for inhibiting viral RNA polymerase activity, viral replication, and treating viral infections.

Synthesis of a C-iminoribofuranoside analog of the nicotinamide phosphoribosyltransferase (NAMPT) inhibitor FK866

Gillig, Annabelle,Majjigapu, Somi Reddy,Sordat, Bernard,Vogel, Pierre

experimental part, p. 34 - 42 (2012/03/07)

FK866 (also named APO866 or WK175) is a potent NAMPT inhibitor being evaluated (Phase II) as a potential anticancer drug. The preparation of the C-iminoribofuranoside analog (2E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-{3- [(2S,3S,4R,5R)-3,4-dihydroxy-5-(h

Process for preparing 2-pyrrolidinyl-1H-pyrrolo[3,2-d]pyrimidine inhibitors of nucleoside metabolism

-

Page column 18, (2008/06/13)

A process of preparing a compound of the formula (I) wherein B is chosen from OH, NH2, NHR, H or halogen; D is chosen from OH, NH2, NHR, H halogen or SCH3; R is an optionally substituted alkyl, aralkyl or aryl group; and Z is selected from OH, hydrogen, halogen, hydroxy, SQ or OQ, Q is an optionally substituted all, aralkyl or aryl group; or a tautomer thereof; or a pharmaceutically acceptable salt thereof; or an ester thereof; or a prodrug thereof, which comprises reacting a compound of the formula (II) ?with an anion produced by abstraction of the bromine or iodine atom from a compound of formula (XIX), ?to form a compound of formula (XX) The compound of formula (XX) is N- and O-deprotected to obtain the compound of formula (I).

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