153185-20-7

Upstream product

• 32934-24-0 S-ethyl 2,3,4,6-tetra-O-acetyl-1-deoxy-1-thio-α-D-mannopyranoside 
• 4163-65-9 per-O-acetyl-α-D-mannopyranose 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 142924-31-0 S-ethyl 4,6-O-benzylidene-1-thio-α-D-mannopyranoside 

Downstream Products

• 153185-21-8 ethyl 4,6-O-benzylidene-2-O-p-methoxybenzyl-3-O-t-butyldimethylsilyl-1-thio-α-D-mannopyranoside 
• 289057-09-6 ethyl 2-O-benzyl-4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-1-thio-α-D-mannopyranoside 

Relevant academic research and scientific papers

A versatile approach to the synthesis of glycans containing mannuronic acid residues

Reported herein is a new method for a highly effective synthesis of β-glycosides from mannuronic acid donors equipped with the 3-O-picoloyl group. The stereocontrol of glycosylations was achieved by means of the H-bond-mediated aglycone delivery (HAD). The method was utilized for the synthesis of a tetrasaccharide linkedviaβ-(1 → 3)-mannuronic linkages. We have also investigated 3,6-lactonized glycosyl donors that provided moderate to high β-manno stereoselectivity in glycosylations. A method to achieve complete α-manno stereoselectivity with mannuronic acid donors equipped with 3-O-benzoyl group is also reported.

SYNTHESIS OF OLIGOSACCHARIDES CORRESPONDING TO STRUCTURES FOUND IN CAPSULAR POLYSACCHARIDES OF CRYPTOCOCCUS NEOFORMANS. PART 1.

Syntheses are described of two trisaccharides, 2-(p-trifluoroacetamidophenyl)ethyl O-(β-D-xylopyranosyl)-(1->2)-O-(α-D-mannopyranosyl)-(1->3)α-D-mannopyranoside (10) and 2-(p-trifluoroacetamidophenyl)ethyl O-(α-D-mannopyranosyl)-(1->3)-O-(β-D-xylopyranos