153186-37-9

Upstream product

• 76227-09-3 (R)-2-benzyloxy-3-hydroxy-propionaldehyde 
• 1439-36-7 1-triphenylphosphoranylidene-2-propanone 

Downstream Products

• 183795-71-3 Ethenesulfonic acid (E)-(S)-2-benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-hexa-3,5-dienyl ester 
• 183795-68-8 Ethenesulfonic acid (E)-(S)-2-benzyloxy-5-trimethylsilanyloxy-hexa-3,5-dienyl ester 
• 183795-62-2 Ethenesulfonic acid (E)-(S)-2-benzyloxy-5-oxo-hex-3-enyl ester 
• 153186-41-5 Ethyl (2R,3R,4R,5S)-4-acetyl-3-<(1S)-1-(benzyloxy)-2-hydroxyethyl>-5-phenylpyrrolidine-2-carboxylate 

Relevant academic research and scientific papers

Diastereofacial selectivity of the cycloaddition of diazo compounds to enones

Chiral α,β-unsaturated γ-alkoxy- or γ-amino-ketones (enones) 1 react with diazo compounds in a stereoselective manner affording conjugated Δ2-pyrazolines 5 and 6. In all cases syn-selectivity for the cycloaddition was observed. The diastereomer

Synthesis of enantiomerically pure pyrrolidines by stereospecific cycloaddition of azomethine ylides with enones

Several (E)-α,β-unsaturated ketones (enones) 2 bearing a chiral alkoxy or amino substituent in γ-position react with azomethine ylides 3 (obtained from glycine imines) in the presence of DBU/ AgOAc giving enantiomerically pure pyrrolidine derivatives 4 in