153198-45-9

Upstream product

• 87269-78-1 undecylidenetriphenylphosphorane 
• 153198-44-8 (5R,8R,8aS)-8-Benzyloxy-3-oxo-hexahydro-oxazolo[3,4-a]pyridine-5-carbaldehyde 
• 693-67-4 bromoundecane 
• 153198-42-6 (1S,2R,5R)-2-benzyloxy-5-(trityloxy)methyl-6-aza-8-oxabicyclo<4.3.0>nonan-7-one 
• 153198-43-7 (1S,2R,5R)-2-benzyloxy-5-hydroxymethyl-6-aza-8-oxabicyclo<4.3.0>nonan-7-one 
• 60669-22-9 n-undecyltriphenylphosphonium bromide 

Relevant academic research and scientific papers

Stereoselective total syntheses of (-)-desoxoprosopinine and (-)-desoxoprosophylline: Palladium(0)-catalyzed intramolecular N-alkylation for the key piperidine ring formation

Intramolecular N-alkylation of D-glucose-derived substrate 21E proceeded in an S(N)2' mode smoothly in the presence of a Pd(0) catalyst and n-Bu4NI. The major cyclization product, a 2,6-dialkylated piperidine 22t, was effectively converted into the title alkaloids.