153235-86-0Relevant academic research and scientific papers
Phosphotriester type biologically active compounds
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, (2008/06/13)
Compounds of formula RO--P(=O)(OR)--Nu where: each R is, independently, --(CH2)n --S--X; X is --C(=Z) (Y) or --S--U; Z is O or S; Y and U are alkyl, aryl or saccharide groups optionally substituted with OH, SH or NH groups; n is 1 to 4; and Nu is a nucleoside which comprises a ribose or deoxyribose sugar portion covalently bound to a base portion.
Biologically active phosphotriester-type nucleosides and methods for preparing same
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, (2008/06/13)
Compounds of formula RS--P(=O) (QR)--Nu where: R is a radical --(CH2)n-W--X; X is a radical --C(=Z) (Y) or --S--U; Z is O or S; W is O or S; Q is O or S; Y and U are an alkyl, aryl or saccharide radical which is optionally substituted with, for example, an OH, SH or NH group; n is equal to 1 to 4, preferably 1 or 2; and Nu is a radical consisting of a residue of a biologically active compound or the dephosphorylated residue of a compound which is biologically active when it bears a phosphate or phosphonate group.
