153258-95-8Relevant academic research and scientific papers
A facile and effective procedure for the synthesis of 4-thiazolidinone derivatives using Y(OTf)3 as catalyst
Luo, Juan,Zhong, Zijun,Ji, Hongfu,Chen, Jiayin,Zhao, Jun,Zhang, Furen
, p. 438 - 449 (2016/07/23)
ABSTRACT: A one-pot three-component reaction for the synthesis of 4-thiazolidinone derivatives has been established by reacting readily available and inexpensive starting materials of amines, aldehydes and thioglycolic acid using Y(OTf)3 (5 mol%) as catalyst in tetrahydrofuran. This method is very efficient due to low catalyst loading and mild reaction conditions and provides an efficient and promising synthetic strategy for the construction of the thiazolidinone skeleton.
SYNTHESIS, SPECTRAL STUDIES AND C-S BOND FISSION THROUGH PUMMERER REACTION OF SOME ALKYLDIACETATES
Gohar, Gamal A.
, p. 171 - 178 (2007/10/02)
A series of methyl and ethyldiacetates have been synthesized and their structures were identified.Correlation between δ-values of the benzylidene protons and ?-Hammett values has been found.The internal chemical shift Δν of the methylene protons was found to be correlated linearly with ?-Hammett constants indicating that the sulfur atom could transmit a polar effect to the substituent.Studies of H2O2 oxidation suggested that a competition between Pummerer and elimination reactions of the intermediate was involved. Key words: Benzylidene dithio diacetates; (1)HNMR spectra; Pummerer reaction
