15329-05-2Relevant academic research and scientific papers
First general method for direct formylation of kinetically-generated ketone enolates
Zayia, Gregory H.
, p. 989 - 991 (2008/02/09)
(matrix presented) 2,2,2-Trifluoroethyl formate reacts rapidly at -78°C with preformed ketone enolates to give α-formyl ketones in good yields. In addition, this procedure allows for complete reversal of the regioselectivity of the classical Claisen react
Biaryles dissymetriques par diformylation et aromatisation de cyclohexen-2-ones.
Labidalle, S.,Jean, E.,Moskowitz, H.,Miocque, M.,Thal,C.
, p. 2869 - 2870 (2007/10/02)
The classical procedure of formylation of ketones is reinvestigated in order to provide a synthetic route to unsymmetrical biaryls from cyclohexenones.
