15330-50-4Relevant academic research and scientific papers
PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS
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Paragraph 0853; 0854; 1869; 1870; 0913; 0914, (2018/07/05)
Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.
AZA-ARYL 1H-PYRAZOL-1-YL BENZENE SULFONAMIDES
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Paragraph 0124; 0125, (2018/02/28)
Compounds are provided that act as potent antagonists of the CCR(9) receptor for treating Sjogren's syndrome. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions.
CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF
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Paragraph 0849, (2018/04/17)
Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.
AZA-ARYL 1H-PYRAZOL-1-YL BENZENE SULFONAMIDES
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Paragraph 0127; 0128, (2013/09/12)
Compounds are provided that act as potent antagonists of the CCR(9) receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR(9). The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR(9)-mediated diseases, and as controls in assays for the identification of CCR(9) antagonists.
