153356-71-9Relevant academic research and scientific papers
Synthesis and biological activity of C-3' ortho dihydroxyphthalimido cephalosporins
Baudart,Hennequin
, p. 1458 - 1470 (2007/10/02)
A series of C-3' ortho dihydroxyphthalimido cephalosporins 3~7 has been prepared by reaction of C-3' aminomethyl cephalosporin 411) with the corresponding N carboethoxyphthalimides 23 ~ 25, 37, 38. These new caphalosporins exhibit excellent in vitro Gram-negative activities, including Pseudomonas aeruginosa, excellent β-lactamases stability and pharmacokinetics equivalent or better than ceftriaxone.
