153372-38-4

Upstream product

• 185250-10-6 Ir(H)2F(P(t)Bu₂Ph)2 
• 1529-17-5 phenyltrimethylsilyl ether 
• 61663-64-7 Ir(H)2Cl(P(t)Bu₂Ph)2 
• 100-67-4 potassium phenolate 
• 204756-52-5 Ir(H)2(NCS)(P(C(CH₃)3)2C₆H₅)2 

Downstream Products

• 208665-14-9 Ir(H)(P(C₄H₉)2C₆H₅)(CO)2 

Relevant academic research and scientific papers

Silyl reagents (Me3Si-X) efficiently transfer X to Ir(H)2F(PtBu2Ph)2

Me3Si-X reagents react to completion at 25°C in a short time to convert Ir(H)2FL2 (L = PtBu2Ph) to Ir(H)2XL2. This involves formation of Ir-O, Ir-N, Ir-I, Ir-S and Ir-C(sp) bonds. Products include some η2-X ligands such as carboxylate and acetamide, NHC(O)CH3. The acetamide is shown to be η2 in the solid state and in solution, but readily rearranges, by a transition state with Ir-O bond cleavage, to effect site exchange of the two inequivalent hydrides. The same synthetic approach succeeds for the more crowded metallated species and these reactions are shown to fail when F is replaced by Cl in the iridium reagent. Unsaturation at Ir is suggested to be central to the mechanism of these F/X transposition reactions.