153392-54-2Relevant academic research and scientific papers
REARRANGEMENT OF ISOXAZOLINE-5-SPIRO DERIVATIVES. IX. sYNTHESIS OF MEDIUM-SIZE AZAHETEROCYCLES
Occhiato, Ernesto G.,Guarna, Antonio,Sarlo, Francesco de,Brandi, Alberto,Goti, Andrea,et al.
, p. 425 - 430 (2007/10/02)
1,3-dipolar cycloaddition of benzonitrile oxide, 1, to 3-methyl-2,3,5,6-tetrahydro-7(1H)-indolizinone, 9, afforded the unexpected tetracyclic adduct 12.The crystal structure of compound 12 has been determined by single crystal X-ray diffraction analysis.T
Ring-Opening of Isoxazolidine Nucleus by Trimethyl Phosphate Treatment: Formation of Tertiary Allylic Alcohols via Intermediate 1,3-Oxazinium Salts
Chiacchio, Ugo,Liguori, Angelo,Romeo, Giovanni,Sindona, Giovanni,Uccella, Nicola
, p. 799 - 817 (2007/10/02)
5,5-Disubstituted isoxazolidines undergo ring opening reaction, leading to tertiary allylic alcohols, by sequential treatment with trimethyl phosphate (TMP) and NaH.The reaction proceeds through sequence steps which involve an initial alkylation to isoxaz
