153402-90-5

Upstream product

• 101979-49-1 (E,R)-3-hydroxy-1-((S)-4-isopropyl-2-thioxothiazolidin-3-yl)-5-phenylpent-4-en-1-one 
• 153402-92-7 (E)-(R)-1-((S)-4-Isopropyl-2-thioxo-thiazolidin-3-yl)-5-phenyl-3-triisopropylsilanyloxy-pent-4-en-1-one 

Downstream Products

• 153402-94-9 (S)-4-Benzyl-3-((E)-(2S,3R,4R,5R,7R)-3,5-dihydroxy-2,4-dimethyl-9-phenyl-7-triisopropylsilanyloxy-non-8-enoyl)-oxazolidin-2-one 
• 153402-95-0 (3S,4R,5S,6R)-4-Hydroxy-3,5-dimethyl-6-((E)-(R)-4-phenyl-2-triisopropylsilanyloxy-but-3-enyl)-tetrahydro-pyran-2-one 
• 153402-93-8 (E)-(2S,4R,5R,7R)-1-((S)-4-Benzyl-2-oxo-oxazolidin-3-yl)-5-hydroxy-2,4-dimethyl-9-phenyl-7-triisopropylsilanyloxy-non-8-ene-1,3-dione 

Relevant academic research and scientific papers

The Synthesis of a C1-C8 Lactone Fragment of Discodermolide

The asymmetric synthesis of a fragment corresponding to the C1-C8 region of the immunosuppressant discodermolide is reported.A trihydroxylactone of defined absolute stereochemistry is also prepared.This compound is a potential reductive ozonolysis product of discodermolide and may aid the determination of the absolute stereochemistry of the natural product.