153403-53-3

Basic information

• Product Name: 2-Chloro-6-fluorobenzo[d]oxazole
• Synonyms: 2-Chloro-6-fluorobenzo[d]oxazole
• CAS NO: 153403-53-3
• Molecular Formula: C₇H₃ClFNO
• Molecular Weight: 171.5562232
• Mol File: 153403-53-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 206.9±13.0 °C(Predicted)
• Appearance: /
• Density: 1.482±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: -0.83±0.30(Predicted)
• CAS DataBase Reference: 2-Chloro-6-fluorobenzo[d]oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-6-fluorobenzo[d]oxazole(153403-53-3)
• EPA Substance Registry System: 2-Chloro-6-fluorobenzo[d]oxazole(153403-53-3)

Safety Data

• Hazardous Substances Data: 153403-53-3(Hazardous Substances Data)

Usage

General Description

2-Chloro-6-fluorobenzo[d]oxazole is a chemical compound with the molecular formula C7H3ClFNO. It is a heterocyclic compound belonging to the oxazole class of organic compounds. This chemical is characterized by a chlorine atom attached to the second carbon atom of the benzene ring and a fluorine atom attached to the sixth carbon atom. It is used in the pharmaceutical industry for the synthesis of various biologically active compounds, including potential drugs. Its unique structure and properties make it a valuable building block for the development of new pharmaceuticals and agrochemicals. Additionally, research is ongoing to explore its potential applications in other fields, such as materials science and organic synthesis.

Upstream product

• 145096-57-7 6-fluoro-1,3-benzoxazole-2-thiol 
• 53981-24-1 2-amino-5-fluorophenol 
• 145096-57-7 6-fluorobenzo[d]oxazole-2(3H)-thione 

Downstream Products

• 1334386-21-8 (R)-2-(6-fluorobenzoxazol-2-ylamino)-3-tritylsulfanyl-propionic acid 
• 1374820-09-3 C₁₇H₁₆Cl₂FN₃O 
• 1147871-54-2 C₁₈H₂₆FN₃O₃S 

Relevant articles and documents

NOVEL COMPOUNDS AND COMPOSITIONS FOR INHIBITION OF FASN

The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:

Analgesic Compounds, Compositions, and Uses Thereof

The invention relates to compounds, compositions, and methods for diminishing pain in a subject in need thereof comprising administering the compounds and compositions herein described.

Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: Heterocyclic P3

A series of Nα-2-benzoxazolyl-α-amino acid-(arylaminoethyl)amides were identified as potent, selective, and noncovalent inhibitors of cathepsin S. Structure-activity relationships including strategies for modulating the selectivities among cathepsins S, K, and L, and in vivo pharmacokinetics are discussed. A X-ray structure of compound 3 bound to the active site of cathepsin S is also reported.