153438-36-9

Downstream Products

• 157437-14-4 2-(3-trifluoromethylbenzoyl)nicotinic acid (4-trifluoromethylphenyl)hydrazone 
• 157437-15-5 2-(3-trifluoromethylbenzoyl)nicotinic acid (2,6-dichloro-4-trifluoromethylphenyl)hydrazone 

Relevant academic research and scientific papers

Benzopyridazinone and pyridopyridazinone compounds

Benzo or pyridopyridazinones and pyridazinthiones of the formula STR1 wherein: X and Y are nitrogen or carbon, provided that at least one is carbon, and Z is oxygen or sulfur; R1 is hydrogen, lower alkyl, aryl, aralkyl, heterocyclo, heterocyclo lower-alkyl, heteroaryl, or heteroaralkyl; R2, R3, R4, R5 and R6 are independently selected from hydrogen, lower alkyl, halo, carboxy, alkoxycarbonyl, carbamoyl, lower-alkyl carbonyl, halocarbonyl, thiomethyl, trifluoromethyl, cyano or nitro; or a pharmaceutically acceptable ester, ether or salt thereof, have been found to be useful as an anti-inflammatory, antasthmatic, immunosuppressive, anti-allograft rejection, anti-graft-vs-host rejection, autoimmune disease or analgetic agent(s).

Nicotinic acid hydrazone compounds which have useful herbicidal compositions

The invention relates to nicotinic acid hydrazone derivatives of formula I: STR1 in which the various symbols are as defined in the description, and their use as herbicides or as intermediates in the synthesis of herbicides.

Herbicidal pyridopyridazinones and pyridopyridazinethiones

Pyrido[2,3-d]pyridazin-5-one and pyrido[2,3-d]pyridazin-5-thione derivatives of general formula (I): STR1 wherein R and R1 independently represent hydrogen, optionally halogenated alkyl, alkenyl or alkynyl, optionally substituted heterocycle or a group --[CR41 R42 ]n -(phenyl)-(R3)q ; R2 represents halogen, optionally halogenated alkyl, alkenyl or alkynyl, CN; --CO2 R4 ; --S(O)r R4 ; --NO2 ; --NR41 R42 ; --OH; --COR4, --S(O)r R5, --CO2 R5, --OR5 ; --CONR41 R42, --OSO2 R5, --OSO2 R6, --OCH2 R5, --N(R41)COR6, --N(R41)SO2 R5, --N(R41)SO2 R6, --SO2 NR41 R42, optionally substituted phenyl, alkoxy or haloalkoxy; X represents oxygen or sulphur; R3 represents halogen, optionally halogenated alkyl, alkenyl, alkoxy, alkynyl, --OH, --S(O)r R4, --CO2 R4, COR4, --CN, --NO2, --NR41 R42, --OR5 ; --CONR41 R42, --OSO2 R5, --OSO2 R6, --OCH2 R5, --N(R41)COR6, --N(R41)SO2 R5, --N(R41)SO2 R6 or --SO2 NR41 R42 ; R4 represents a hydrogen atom or optionally halogenated C1-6 alkyl; R41 and R42, which may be the same or different, each represents a hydrogen atom or optionally halogenated C1-4 alkyl; R5 represents a phenyl group optionally substituted by from one to five groups selected from halogen, nitro, cyano, R4 and --OR4 ; m represents zero or an integer from one to three; n represents zero, one or two; where n is two, the groups --(CR41 R42)-- may be the same or different; q represents zero or an integer from one to five; r represents zero, one or two; with the proviso that when m represents zero R and R1 do not simultaneously represent hydrogen; and agriculturally acceptable salts thereof are useful as herbicides.