15346-08-4Relevant academic research and scientific papers
Asymmetric construction of six vicinal stereogenic centers on hexahydroxanthonesviaorganocatalytic one-pot reactions
He, Xue-Wen,Liu, Xiong-Li,Xiong, Ya,Zhang, Min,Zhou, Wei,Zuo, Xiong
supporting information, p. 6764 - 6767 (2021/07/13)
Inspired by the chemistry and biology of hexahydroxanthones, herein we report an organocatalytic Michael-Michael-Aldol-decarboxylation reaction that provides efficient access to biologically interesting fully substituted hexahydroxanthones bearing six contiguous stereogenic centers from readily accessible materials in acceptable yields (up to 63%) and excellent stereoselectivities (up to 10?:?1 dr and >99% ee). In other words, the reaction efficiently produces three chemical bonds and up to six vicinal stereogenic centers in a one-pot operation. In particular, to our knowledge, this is an asymmetric organocatalytic strategy enabling the first construction of six vicinal stereogenic centers on non-spirocyclic hexahydroxanthone frameworks.
Synthesis, characterization, NLO study, and antimicrobial activities of metal complexes derived from 3-(3-(2-hydroxyphenyl)-3-oxoprop-1-enyl)-4H- chromen-4-one and sulfanilamide
Sumathi,Tharmaraj,Sheela,Ebenezer,Saravana Bhava
scheme or table, p. 1673 - 1682 (2012/02/04)
A series of metal(II) complexes ML (where M = Cu(II), Co(II), Ni(II), Zn(II), Mn(II), Cd(II), and VO(II)) have been prepared from 3-(3-(2- hydroxyphenyl)-3-oxoprop-1-enyl)-4H-chromen-4-one and sulfanilamide. The structures of the complexes have been inves
Synthesis and evaluation of potential pharmacophores derived from 4-oxo-4H-1-benzopyran-3-carboxaldehyde
Coutinho, Dionysia L M,Fernandes, Peter S
, p. 573 - 577 (2007/10/02)
The preparation of hydrazone derivatives of 4-oxo-4H-1-benzopyran-3-carboxaldehyde (2a-c, 4a-c, 5, 6a,b), 3-aryl-1-(benzopyran-4-one-3-yl)-propen-3-one (8a-c), ethyl 2-cyano-3-(benzopyran-4-one-3-yl)acrylate (10) and thioacetal derivatives of 4-oxo-4H-1-b
Synthese de 2-pyrimidinylphenols et de 2-pyrazolylphenols
Sacquet, Marie-Claude,Fargeau-Bellassoued, Marie Claude,Graffe, Bernadette
, p. 667 - 672 (2007/10/02)
De nouveaux pyrimidinylphenols 9a-e et pyrazolylphenols 10a-e substitues par des groupes aminomethyles sont prepares avec de bons rendements par action respective du carbonate de guanidine et de l'hydrate d'hydrazine sur les 3-aminomethylchromones 8a-e.Ces 3-aminomethylchromones 8a-e sont aisement obtenues par reaction de Mannich sur la chromone 5.Les rendements en chromone 5 et en aminomethylchromones 8a-e ont ete notablement ameliores.
