153476-68-7 Usage
Uses
Used in Pharmaceutical Industry:
2-Chloromethyl-3,5-dimethyl-4-nitropyridine is used as a chemical intermediate in the synthesis of various drugs. Its reactivity allows it to participate in a range of chemical reactions, which is essential for creating more complex molecules that can be used in medicinal chemistry.
Used in Chemical Reactions:
Due to its distinctive functional groups, 2-chloromethyl-3,5-dimethyl-4-nitropyridine is employed in various chemical reactions to form more complex molecules. Its versatility in these reactions makes it a valuable compound in the field of organic chemistry.
Safety Considerations:
special care must be taken in the handling and storage of 2-chloromethyl-3,5-dimethyl-4-nitropyridine to minimize potential risks associated with its reactivity. Proper safety measures should be implemented to ensure the safe use of 2-CHLOROMETHYL-3,5-DIMETHYL-4-NITROPYRIDINE in research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 153476-68-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,4,7 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 153476-68:
(8*1)+(7*5)+(6*3)+(5*4)+(4*7)+(3*6)+(2*6)+(1*8)=147
147 % 10 = 7
So 153476-68-7 is a valid CAS Registry Number.
153476-68-7Relevant academic research and scientific papers
NEW METHOD FOR THE PREPARATION OF THE ANTI-ULCER COMPOUNDS OMEPRAZOLE, LANSOPRAZOLE AND PANTOPRAZOLE
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Page/Page column 11, (2010/02/07)
The present invention describes a new process for the preparation of omeprazole, lansoprazole and pantoprazole of formula (XXI), (XXXIII), and which involves the formation of pyridines N-oxide using a rhenium compound as a catralyst, followed by nitration of the 4-position with nitric acid fuming in presence of a claycop. The chlorination of the 2-methyl group of pyridine was achieved by using the POCI3/Et3N, which allowed the preparation of the derivates 2-chloromethylpyridines in only one step. These derivates reacted with the mercaptobenzimidazolic derivatives in presence of ultra-sonic radiation, giving the thioethers. The oxidation of these thioethers was done with several oxidizing agents and the required anti-ulcer compounds were obtained after the substitution of nitro group by the corresponding OR groups.
