1535-32-6

Basic information

• Product Name: 3-chlorophenyl fluorosulfonate
• Synonyms: 3-chlorophenyl fluorosulfonate
• CAS NO: 1535-32-6
• Molecular Weight: 210.613
• Mol File: 1535-32-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-chlorophenyl fluorosulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chlorophenyl fluorosulfonate(1535-32-6)
• EPA Substance Registry System: 3-chlorophenyl fluorosulfonate(1535-32-6)

Safety Data

• Hazardous Substances Data: 1535-32-6(Hazardous Substances Data)

Upstream product

• 108-43-0 3-monochlorophenol 

Downstream Products

• 2051-61-8 m-chlorobiphenyl 
• 587-04-2 m-Chlorobenzaldehyde 
• 625-98-9 3-chlorofluorobenzene 
• 101-17-7 3-chlorodiphenylamine 
• 36383-13-8 1-(sec-butyl)-3-chlorobenzene 

Relevant articles and documents

Continuous flow synthesis of aryl aldehydes by Pd-catalyzed formylation of phenol-derived aryl fluorosulfonates using syngas

This communication describes the palladium-catalyzed reductive carbonylation of aryl fluorosulfonates (ArOSO2F) using syngas as an inexpensive and sustainable source of carbon monoxide and hydrogen. The conversion of phenols to aryl fluorosulfonates can be conveniently achieved by employing the inexpensive commodity chemical sulfuryl fluoride (SO2F2) and base. The developed continuous flow formylation protocol requires relatively low loadings for palladium acetate (1.25 mol%) and ligand (2.5 mol%). Good to excellent yields of aryl aldehydes were obtained within 45 min for substrates containing electron withdrawing substituents, and 2 h for substrates containing electron donating substituents. The optimal reaction conditions were identified as 120 °C temperature and 20 bar pressure in dimethyl sulfoxide (DMSO) as solvent. DMSO was crucial in suppressing Pd black formation and enhancing reaction rate and selectivity. This journal is