1535200-75-9Relevant academic research and scientific papers
Synthesis and evaluation of 4-substituted piperidines and piperazines as balanced affinity μ opioid receptor (MOR) agonist/δ opioid receptor (DOR) antagonist ligands
Bender, Aaron M.,Clark, Mary J.,Agius, Michael P.,Traynor, John R.,Mosberg, Henry I.
, p. 548 - 551 (2014/01/23)
In this letter, we describe a series of 4-substituted piperidine and piperazine compounds based on tetrahydroquinoline 1, a compound that shows balanced, low nanomolar binding affinity for the mu opioid receptor (MOR) and the delta opioid receptor (DOR).
