153628-67-2

Upstream product

• 153628-72-9 (Z)-(4R,5S,6R)-7-Benzyloxy-2,4,6-trimethyl-5-triisopropylsilanyloxy-hept-2-enoic acid ethyl ester 
• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 79026-61-2 (R)-3-benzyloxy-2-methylpropanal 
• 101712-01-0 (R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-2-methylpentane-1,3-dione 
• 153628-60-5 (5R,6S)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-3,5-dimethyl-5,6-dihydro-pyran-2-one 
• 153628-61-6 (Z)-(4R,5S,6R)-7-Benzyloxy-2,4,6-trimethyl-hept-2-ene-1,5-diol 
• 153628-59-2 (3R,4R,5R,6R)-6-((R)-2-Benzyloxy-1-methyl-ethyl)-4-hydroxy-3,5-dimethyl-tetrahydro-pyran-2-one 
• 153628-69-4 (S)-4-Benzyl-3-((2S,3R,4R)-5-benzyloxy-2,4-dimethyl-3-triisopropylsilanyloxy-pentanoyl)-oxazolidin-2-one 
• 153628-58-1 (R)-4-Benzyl-3-((2R,3R,4S,5R,6R)-7-benzyloxy-3,5-dihydroxy-2,4,6-trimethyl-heptanoyl)-oxazolidin-2-one 
• 153628-57-0 (2R,4S,5R,6R)-1-((R)-4-Benzyl-2-oxo-oxazolidin-3-yl)-7-benzyloxy-5-hydroxy-2,4,6-trimethyl-heptane-1,3-dione 
• 153628-68-3 (S)-4-Benzyl-3-((2S,3R,4R)-5-benzyloxy-3-hydroxy-2,4-dimethyl-pentanoyl)-oxazolidin-2-one 
• 153628-70-7 (2S,3R,4R)-5-Benzyloxy-2,4-dimethyl-3-triisopropylsilanyloxy-pentanethioic acid S-benzyl ester 
• 153628-62-7 2,2-Dimethyl-propionic acid (Z)-(4R,5S,6R)-7-benzyloxy-5-hydroxy-2,4,6-trimethyl-hept-2-enyl ester 
• 153628-71-8 (2S,3R,4R)-5-Benzyloxy-2,4-dimethyl-3-triisopropylsilanyloxy-pentanal 

Downstream Products

• 153628-64-9 (S)-4-Benzyl-3-((Z)-(2R,6R,7S,8R)-9-benzyloxy-2,4,6,8-tetramethyl-7-triisopropylsilanyloxy-non-4-enoyl)-oxazolidin-2-one 
• 153628-65-0 (Z)-(2R,6R,7S,8R)-9-Benzyloxy-2,4,6,8-tetramethyl-7-triisopropylsilanyloxy-non-4-enethioic acid S-benzyl ester 
• 153628-63-8 [(Z)-(1S,2R)-1-((R)-2-Benzyloxy-1-methyl-ethyl)-5-iodo-2,4-dimethyl-pent-3-enyloxy]-triisopropyl-silane 

Relevant academic research and scientific papers

The synthesis of a C9-C17 fragment of discodermolide

The asymmetric synthesis of a synthetically useful fragment corresponding to the C9-C17 region of the immunosuppressant lactone discodermolide is reported. The route incorporates the use of an unsaturated lactone to provide a trisubstituted olefin with absolute control of geometry.

An approach to the synthesis of a C9-C15 fragment of discodermolide

The asymmetric synthesis of a synthetically useful fragment corresponding to the C9-C15 region of the immunosuppressant lactone discodermolide is reported.