15363-94-7

Basic information

• Product Name: 1,5-dimethyl-2,3-diphenyl-pyrrole
• Synonyms: 1,5-dimethyl-2,3-diphenyl-pyrrole
• CAS NO: 15363-94-7
• Molecular Weight: 247.34
• Mol File: 15363-94-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,5-dimethyl-2,3-diphenyl-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-dimethyl-2,3-diphenyl-pyrrole(15363-94-7)
• EPA Substance Registry System: 1,5-dimethyl-2,3-diphenyl-pyrrole(15363-94-7)

Safety Data

• Hazardous Substances Data: 15363-94-7(Hazardous Substances Data)

Upstream product

• 1817-57-8 4-phenyl-3-butyne-2-one 
• 2392-54-3 (acetyl-methyl-amino)-phenyl-acetic acid 
• 536-74-3 phenylacetylene 
• 3274-32-6 5-methyl-2,3-diphenyl-1H-pyrrole 
• 80-48-8 methyl p-toluene sulfonate 
• 81616-14-0 tert-butyl N-benzyl-N-methylcarbamate 

Downstream Products

• 133110-55-1 (1,2-Dimethyl-4,5-diphenyl-1H-pyrrol-3-yl)-acetic acid ethyl ester 

Relevant articles and documents

A facile synthesis of polysubstituted pyrroles

(equation presented) α-Aminoalkylcuprates prepared from CuX·2LiCI (X = Cl, CN) and 1 equiv of an α-lithiocarbamate undergo conjugate addition reactions to α,β-alkynyl ketones in moderate to good yields, affording E:Z mixtures of α,β-enones. Treatment of the conjugate adducts with PhOH/TMSCI in CH2CI2 effected carbamate deprotection and cyclization to afford a flexible two-step synthesis of substituted pyrroles.

REGIOSELECTIVITY IN THE 1,3-DIPOLAR CYCLOADDITION REACTION OF 3-METHYLOXAZOLIUM 5-OLATES WITH ACETYLENIC DIPOLAROPHILES

The cycloaddition reaction of unsymmetrically substituted munchnones with monosubstituted alkynes has been examined.The reaction affords a mixture of regioisomeric pyrroles.The observed regioselectivity is qualitatively discussed on the basis of the MO-pe