153644-81-6Relevant academic research and scientific papers
Cyclopentane Formation from Flexible Precursors Using Samarium(II) Reagents
Aretz, Christopher D.,Escobedo, Humberto,Cowen, Bryan J.
supporting information, p. 1880 - 1884 (2018/05/09)
Three efficient methods for five-membered ring carbocycle synthesis have been developed from simple starting materials using samarium(II) reagents. A Reformatsky aldol reaction proceeded efficiently with samarium(II) iodide using lithium bromide as an additive. A new intramolecular alkylation of a samarium enolate was realized with a pendant sulfonate ester leaving group. Pinacol cyclization of a simple diketone was also demonstrated giving a diol product in high stereoselectivity. A promising lead result has been established demonstrating enantioselectivity in a chiral ligand controlled Reformatsky aldol reaction.
Highly efficient chromium-catalyzed oxidation of secondary benzylic alcohols by aqueous 70% tert-butyl hydroperoxide
Muzart,N'Ait Ajjou
, p. 785 - 787 (2007/10/02)
The oxidation of secondary benzylic alcohols to ketones by the chromium(VI) oxide/tert-butyl hydroperoxide system is compatible with the presence of methyl, halide, methoxy, acetoxy or nitro substituents on the aryl group and of an unsaturation on the alkyl side chain. Benzyl alcohol led to a mixture of benzaldehyde and benzoic acid.
