153644-97-4Relevant academic research and scientific papers
Stereoselective Hydrogen Transfer Reactions Involving Acyclic Radicals. Tandem Substituted Tetrahydrofuran Formation and Stereoselective Reduction: Synthesis of the C17-C22 Subunit of Ionomycin
Guindon, Y.,Yoakim, C.,Gorys, V.,Ogilvie, W. W.,Delorme, D.,et al.
, p. 1166 - 1178 (2007/10/02)
The tandem iodoetherification reaction and stereoselective reduction of acyclic redicals has been used in the stereocontrolled synthesis of substituted tetrahydrofurans.Such a tetrahydrofuran intermediate is regioselectively cleaved using Me2BBr to reveal
The effect of polar substituents on the conformation and stereochemistry of enolate radicals
Giese,Damm,Wetterich,Zeitz,Rancourt,Guindon
, p. 5885 - 5888 (2007/10/02)
ESR measurements and AM1 calculations show that ester substituted radicals 2 and 6 prefer conformation A as a result of allylic strain effects. But dipolar repulsion between substituents X and CO2Et In 2 and 6 has a pronounced effect on the con
