153645-51-3Relevant academic research and scientific papers
Preparation and characterization of magnetic graphene nanocomposite containing Cu(proline)2 as catalyst for asymmetric aldol reactions
Kooti,Kooshki,Nasiri
, p. 2641 - 2656 (2019/02/14)
A new catalyst has been prepared via immobilization of Cu(proline)2 complex onto the surface of magnetic graphene. The fabricated nanocatalyst was characterized by Fourier-transform infrared (FT-IR) spectroscopy, powder X-ray diffraction (PXRD) analysis, vibrating-sample magnetometry (VSM), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) spectroscopy, transmission electron microscopy (TEM), inductively coupled plasma (ICP) techniques, and elemental analysis. Its catalytic performance was investigated in the aldol reaction using a mild and ecofriendly procedure. The synthesized nanocomposite, which contains Cu(II) center as Lewis acid, was found to be an efficient catalyst for asymmetric aldol reactions, affording corresponding aldol products in high yield and excellent enantiomeric excess (> 90?%). The examined catalyst was prepared from low-cost, easily available starting materials and can be readily isolated by magnetic decantation for recycling and reuse in consecutive reactions without significant loss of activity.
BiCl3-catalyzed Mukaiyama-aldol and carbonyl-ene reactions
Peidro, Laurence,Le Roux, Christophe,Laporterie, Andre,Dubac, Jacques
, p. 397 - 399 (2007/10/03)
The H-ene pathway has not been detected for the bismuth(III) chloride-catalyzed Mukaiyama-aldol reaction involving silyl enol ethers and aldehydes. The silatropic ene-like process is the only mechanism observed, even with the weakly reactive 1-(trimethylsilyloxy) cyclohexene. However, trimerization of an aliphatic aldehyde can occur.
INTERMOLECULAR ALDOL REACTIONS VIA ALLYLIC O-STANNYL KETYLS
Enholm, Eric J.,Whitley, Paul E.
, p. 9157 - 9160 (2007/10/02)
A mild and neutral free radical reaction of an α,β-unsaturated ketone and tributyltin radical produced a resonance-stabilized allylic O-stannyl ketyl intermediate.A tin(IV)enolate, produced by subsequent hydrogen atom transver, was next quenched with various aldehydes to yield an aldol product which was readily eliminated with p-toluenesulfonic acid to afford new α,β-unsaturated ketones with E/Z ratios up to > 100:1.
Lewis acid promoted ene-like reactions of enol ethers with aldehydes
Shoda,Nakamura,Tanino,Kuwajima
, p. 6281 - 6284 (2007/10/02)
Use of organoaluminum reagents induces ene-like reactions of enol silyl ethers with aldehydes, and enols having bulky silyl groups selectively afforded syn adducts.
