153646-83-4

Usage

Uses

Used in Pharmaceutical Industry:
2-Pyridinecarboxaldehyde, 6-(1-methylethyl)(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to form complex molecular structures that can exhibit therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Pyridinecarboxaldehyde, 6-(1-methylethyl)(9CI) is utilized as a precursor in the development of compounds that can protect crops from pests and diseases, leveraging its reactivity and structural diversity.
Used in Flavor and Fragrance Industry:
2-Pyridinecarboxaldehyde, 6-(1-methylethyl)(9CI) is employed as a flavoring agent in the food industry, adding unique taste and aroma profiles to various food products, capitalizing on its strong, pungent odor.
Used in Fine Chemicals Industry:
2-Pyridinecarboxaldehyde, 6-(1-methylethyl)(9CI) is also used in the production of fine chemicals, where its aldehyde group can be further modified or used to create a wide range of specialty chemicals for various applications, such as dyes, coatings, and more.

Upstream product

• 626-05-1 2,6-Dibromopyridine 
• 1068-55-9 isopropylmagnesium chloride 
• 68-12-2 N,N-dimethyl-formamide 
• 153646-82-3 6-ethyl-2-pyridinecarboxaldehyde 

Relevant academic research and scientific papers

Tributylmagnesium ate complex-mediated novel bromine-magnesium exchange reaction for selective monosubstitution of dibromoarenes

Lithium tributylmagnesate complex (n-Bu3MgLi), readily prepared from n-BuLi and n-BuMgCl (2:1), is a novel metallation agent. It is quite efficient for the selective mono-bromine-magnesium exchange of 2,6-dibromopyridine (1) under non-cryogenic conditions (at -10°C) to give a stable magnesate intermediate. Subsequent treatment with DMF gave 6-bromo-2-formylpyridine (3) in excellent yield. This method is also applicable for selective monosubstitution of several other kinds of dibromoarenes.

Pyridin-2-yl-methylamine derivatives, method of preparing and application as medicine

PCT No. PCT/FR97/02097 Sec. 371 Date May 21, 1999 Sec. 102(e) Date May 21, 1999 PCT Filed Nov. 20, 1997 PCT Pub. No. WO98/22459 PCT Pub. Date May 28, 1998The invention concerns novel pyridin-2-yl-methylamine derivatives of formula (I): in which: u represents hydrogen or methyl; v represents hydrogen, chlorine, or methyl; w represents hydrogen, fluorine, or methyl; x represents hydrogen or fluorine; y represents chlorine or methyl; z represents hydrogen, fluorine, chlorine, or methyl; A represents hydrogen, fluorine, chlorine, C1-C5 alkyl, fluoroalkyl, cyclopropyl, a 5-membered aromatic heterocyclic group, alkoxy or alkythio, amino, cyclic amino, or alkoxycarbonyl. These compounds are useful as medicines, in particular as antidepressants or analgesics.

PYRIDINE-SUBSTITUTED BENZYL ALCOHOLS AS LEUKOTRIENE ANTAGONISTS

Compounds having the formula I: STR1 are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.