1536472-72-6Relevant academic research and scientific papers
Discovery of cationic domino reaction under the NMR experiment conditions: Diastereoselective dimerization of 2-arylmethylideneindolin-3-ones to pentacyclic 3-hydroxyindolenine system
Peregudov,Godovikov,Fedorova,Istomina,Lyssenko,Velezheva
, p. 850 - 854 (2013)
NMR spectroscopy (1D and 2D) showed that the protonation of the capto-dative heterocyclic α-amino enones, viz., (Z)-2- arylmethylideneindolin-3-ones, with strong acids led to stable (aryl)(3-hydroxyindol-2-yl)methyl cations. These substrates in trifluoroacetic acid underwent cationic domino reaction, which resulted in polynuclear pyrido[1,2-a: 5,6-b′]-[1,2′]biindoles.
