153685-97-3Relevant articles and documents
2-Substituted 1,3-Benzodiazocines: Design, Synthesis and Evaluation as Potential Central Nervous System Active Agents
Nicholls, Ian A.,Alewood, Paul F.,Brinkworth, Ross I.,Morrison, Stuart F.,Andrews, Peter R.
, p. 2811 - 2826 (2007/10/02)
Hybridisation of the structures of the antihypertensive clonidine 1 with the anxiolytic diazepam 2 led to the novel 2-imino-1,3-benzodiazocine 3.Conformational analysis of 3 and comparison to a previously established pharmacophore for CNS activity reveale