153783-21-2

Upstream product

• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 106-38-7 para-bromotoluene 
• 251924-83-1 1-tert-butyl 2-ethyl 5-oxopyrrolidine-1,2-dicarboxylate 

Downstream Products

• 131172-59-3 5-p-Tolyl-1H-pyrrole-2-carboxylic acid 
• 65117-63-7 2-carbethoxy-5-(4-methylphenyl)pyrrole 
• 153783-26-7 (S)-5-Ethoxycarbonyl-2-(p-tolyl)-Δ¹-pyrroline 

Relevant academic research and scientific papers

Convenient synthesis of C-aza-2,3-dideoxynucleosides

l-Aryl-l,2,3,4-tetradeoxy-l,4-imino-D-pentitols 5 and 9f are easily synthesized from TV-Boc-L-pyroglutamate 1 via a successive procedure involving regioselective ring-opening, recyclization with dehydration, stereoselective reduction, and reduction of the

Design of orally active dual inhibitors of neutral endopeptidase and angiotensin-converting enzyme with long duration of action

Mercaptoacyl dipeptides, containing a glycine linked to a C-terminal 5- phenylproline, have been synthesized in order to obtain new highly efficient dual inhibitors of the two zinc metallopeptidases, neutral endopeptidase (NEP) and angiotensin-converting

General method for the synthesis of 5-arylpyrrole-2-carboxylic acids

5-Arylpyrrole-2-carboxylic acids are prepared by DDQ oxidative aromatization of the corresponding ethyl 2-aryl-Δ1-pyrroline-5-carboxylate followed by basic hydrolysis.