15379-41-6

Basic information

• Product Name: 1-propyl-1,3-dihydro-2H-indol-2-one
• CAS NO: 15379-41-6
• Molecular Formula: C₁₁H₁₃NO
• Molecular Weight: 175.227
• Mol File: 15379-41-6.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 361.023°C at 760 mmHg
• Flash Point: 174.603°C
• Density: 1.094g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.556
• CAS DataBase Reference: 1-propyl-1,3-dihydro-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-propyl-1,3-dihydro-2H-indol-2-one(15379-41-6)
• EPA Substance Registry System: 1-propyl-1,3-dihydro-2H-indol-2-one(15379-41-6)

Safety Data

• Hazardous Substances Data: 15379-41-6(Hazardous Substances Data)

Usage

General Description

1-propyl-1,3-dihydro-2H-indol-2-one, also known as 1-propyltryptone or 1-propyl-1,3-dihydroindol-2-one, is a chemical compound with the molecular formula C11H15NO. It is a derivative of tryptophan, an essential amino acid commonly found in food. 1-propyl-1,3-dihydro-2H-indol-2-one has been studied for its potential pharmaceutical applications, particularly in the treatment of depression and anxiety. It acts as a selective serotonin reuptake inhibitor, meaning it can increase the levels of serotonin in the brain, which is thought to improve mood and alleviate symptoms of these mental health disorders. While further research is needed to fully understand its mechanism of action and potential therapeutic uses, 1-propyl-1,3-dihydro-2H-indol-2-one shows promise as a novel pharmaceutical agent for the management of mood disorders.

Upstream product

• 107-10-8 propylamine 
• 2444-36-2 2'-chloro-benzeneacetic acid 
• 146852-20-2 1-allyl-1,3-dihydro-2H-indol-2-one 
• 91-56-5 indole-2,3-dione 
• 830-74-0 1-allyl-1H-indole-2,3-dione 
• 4290-87-3 1-prop-2-ynyl-1H-indole-2,3-dione 
• 41042-12-0 N-propylisatin 

Downstream Products

• 1596355-38-2 ethyl (3S)-3-[(3S)-2,5-dioxo-1-phenylpyrrolidin-3-yl]-2-oxo-1-propyl-2,3-dihydro-1H-indole-3-carboxylate 

Relevant articles and documents

Selective photo-reduction of 1-alkylisatins in degassed alcoholic solutions

Irradiation of 1-alkylisatins (1) in degassed alcohols afforded 1-alkyl-3-hydroxyoxindoles (2) and 1-alkyloxindoles (3) as chemoselective photoproducts.

New cell cycle checkpoint pathways regulators with 2-Oxo-indoline scaffold as potential anticancer agents: Design, synthesis, biological activities and in silico studies

3-Arylidene-2-oxo-indoline derivatives are at the heart of a wide range of clinically, medicinally and biologically important compounds among the 2-oxo-indolines. A number of 3-arylidene-2-oxo-indolines have been approved for clinical application. Accordi

Annulation reaction of cyclic pyridinium ylides with: In situ generated azoalkenes for the construction of spirocyclic skeletons

Two new types of cyclic pyridinium ylides were designed and further used in reactions with azoalkenes to access structurally diverse spirocyclic compounds. A range of spiropyrazoline oxindoles could be smoothly obtained in up to 99% yield via a [4 + 1] annulation process with oxindole 3-pyridinium ylides as C1 synthons. Similarly, a series of spiropyrazoline indanones could be prepared with indanone 2-pyridinium ylides as C1 synthons. This work represents the first example of cyclic pyridinium ylides as C1 synthons for the efficient construction of spirocyclic compounds.