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1-(2-((3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy)ethyl)-4-(2-methoxyphenyl)piperazine, also known as GSK-3 inhibitor, is a chemical compound utilized in scientific research for studying the inhibition of glycogen synthase kinase 3 (GSK-3). This serine/threonine protein kinase is crucial in various cellular processes such as glycogen metabolism, gene expression, apoptosis, and cell differentiation. 1-(2-((3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy)ethyl)-4-(2-methoxyphe nyl)piperazine has demonstrated potential therapeutic applications in treating diseases like cancer, diabetes, and neurodegenerative disorders. While the exact mechanism of action and possible side effects are still under investigation, it holds promise as a valuable tool for understanding and potentially treating a wide array of medical conditions.

153804-42-3

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153804-42-3 Usage

Uses

Used in Pharmaceutical Research:
1-(2-((3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy)ethyl)-4-(2-methoxyphenyl)piperazine is used as a research tool for studying the inhibition of glycogen synthase kinase 3 (GSK-3) due to its potential therapeutic applications in treating various diseases.
Used in Cancer Treatment Research:
In the field of oncology, 1-(2-((3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy)ethyl)-4-(2-methoxyphenyl)piperazine is used as a potential therapeutic agent for the treatment of various types of cancer, given its ability to inhibit GSK-3, a protein kinase involved in cellular processes relevant to cancer development and progression.
Used in Diabetes Research:
1-(2-((3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy)ethyl)-4-(2-methoxyphenyl)piperazine is used as a research compound for exploring its potential in diabetes treatment, as GSK-3 inhibition may play a role in regulating glucose metabolism and insulin signaling.
Used in Neurodegenerative Disorder Research:
1-(2-((3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy)ethyl)-4-(2-methoxyphe nyl)piperazine is also used in the study of neurodegenerative disorders, given its potential to inhibit GSK-3, which has been implicated in the pathogenesis of conditions such as Alzheimer's and Parkinson's disease.
Used in Drug Development:
1-(2-((3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy)ethyl)-4-(2-methoxyphenyl)piperazine serves as a lead compound in the development of new drugs targeting GSK-3 for the treatment of various medical conditions, including those mentioned above.

Check Digit Verification of cas no

The CAS Registry Mumber 153804-42-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,8,0 and 4 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 153804-42:
(8*1)+(7*5)+(6*3)+(5*8)+(4*0)+(3*4)+(2*4)+(1*2)=123
123 % 10 = 3
So 153804-42-3 is a valid CAS Registry Number.
InChI:InChI=1/C22H28N2O2S/c1-25-20-9-3-2-8-19(20)24-13-11-23(12-14-24)15-16-26-21-10-4-6-18-7-5-17-27-22(18)21/h2-4,6,8-10H,5,7,11-17H2,1H3

153804-42-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[2-(3,4-dihydro-2H-thiochromen-8-yloxy)ethyl]-4-(2-methoxyphenyl)piperazine

1.2 Other means of identification

Product number -
Other names Piperazine,1-(2-((3,4-dihydro-2H-1-benzothiopyran-8-yl)oxy)ethyl)-4-(2-methoxyphenyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:153804-42-3 SDS

153804-42-3Downstream Products

153804-42-3Relevant academic research and scientific papers

THIOCHROMAN COMPOUNDS

-

, (2008/06/13)

The invention relates to compounds of the formula I: STR1 in which R 1 is as defined in the description, their optical isomers and their addition salts with a pharmaceutically-acceptable acid or base, andmedicinal products which are useful for treating Central Nervous System disorders.

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