15386-95-5Relevant articles and documents
Discovery of a Potent Inhibitor Class with High Selectivity toward Clostridial Collagenases
Sch?nauer, Esther,Kany, Andreas M.,Haupenthal, J?rg,Hüsecken, Kristina,Hoppe, Isabel J.,Voos, Katrin,Yahiaoui, Samir,Els?sser, Brigitta,Ducho, Christian,Brandstetter, Hans,Hartmann, Rolf W.
supporting information, p. 12696 - 12703 (2017/09/25)
Secreted virulence factors like bacterial collagenases are conceptually attractive targets for fighting microbial infections. However, previous attempts to develop potent compounds against these metalloproteases failed to achieve selectivity against human