153870-19-0

Basic information

• Product Name: benzyl (2S)-2-(hydroxymethyl)-5-oxopyrrolidine-1-carboxylate
• Synonyms: benzyl (2S)-2-(hydroxymethyl)-5-oxopyrrolidine-1-carboxylate
• CAS NO: 153870-19-0
• Molecular Weight: 249.266
• Mol File: 153870-19-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: benzyl (2S)-2-(hydroxymethyl)-5-oxopyrrolidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2S)-2-(hydroxymethyl)-5-oxopyrrolidine-1-carboxylate(153870-19-0)
• EPA Substance Registry System: benzyl (2S)-2-(hydroxymethyl)-5-oxopyrrolidine-1-carboxylate(153870-19-0)

Safety Data

• Hazardous Substances Data: 153870-19-0(Hazardous Substances Data)

Upstream product

• 17342-08-4 (S)-Pyroglutaminol 
• 106191-02-0 (S)-5-((tert-butyldimethylsilyloxy)methyl)pyrrolidin-2-one 
• 32159-21-0 Cbz-L-pGlu-OH 
• 153870-09-8 (S)-1-(benzyloxycarbonyl)-5-[(tert-butyldimethylsilyl)oxymethyl]-2-pyrrolidinone 

Downstream Products

• 1422064-17-2 1-(3-{(2R)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl}propyl)-1H-imidazole-4-carboxylic acid 
• 1422064-16-1 1-(3-{(2R)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl}propyl)-1H-imidazole-5-carboxylic acid 
• 1422064-15-0 benzyl 1-(3-{(2R)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl}propyl)-1H-imidazole-4-carboxylate 
• 1422064-14-9 benzyl 1-(3-{(2R)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl}propyl)-1H-imidazole-5-carboxylate 
• 1422064-13-8 (5R)-5-[3-(1H-imidazol-1-yl)propyl]-1-[4-(2-methoxyethoxy)benzyl]-pyrrolidin-2-one 
• 1422064-12-7 3-{(2R)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl}propyl 4-methylbenzenesulfonate 
• 1422064-11-6 (5R)-5-(3-hydroxypropyl)-1-[4-(2-methoxyethoxy)benzyl]-pyrrolidin-2-one 
• 1422064-08-1 benzyl (2S)-2-[(1E)-3-methoxy-3-oxoprop-1-en-1-yl]-5-oxopyrrolidine-1-carboxylate 
• 1422064-10-5 methyl 3-{(2S)-1-[4-(2-methoxyethoxy)benzyl]-5-oxopyrrolidin-2-yl} propanoate 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 
• 153870-06-5 (2S,5S)-2-Hydroxymethyl-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 153870-09-8 (S)-1-(benzyloxycarbonyl)-5-[(tert-butyldimethylsilyl)oxymethyl]-2-pyrrolidinone 
• 382141-48-2 (1R,2S,3R,6S)-2-{2-[(E)-tert-Butylimino-methyl]-butyryl}-3-hydroxy-9-aza-bicyclo[4.2.1]nonane-9-carboxylic acid benzyl ester 
• 382141-43-7 2-(4-tert-butoxycarbonyl-3-oxo-butyl)-5-methoxy-pyrrolidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

Unprecedented migration of N-alkoxycarbonyl groups in protected pyroglutaminol.

[figure: see text] Cleavage of an O-silyl ether in an N-BOC-protected pyroglutaminol using TBAF led to an unprecedented migration of the BOC group. An investigation of the mechanism, based on experimental data and quantum mechanical calculations, is presented. Similar migration was observed for N-Cbz and N-methoxycarbonyl groups.

Pyrrolidine based analogs of 3′-deoxythymidine

Pyrrolidine based analogs of 3′-deoxythymidine la,b and 2a,b have been prepared via N-acyliminium ion intermediates 3 and 4.