153875-87-7 Usage
Uses
Used in Pharmaceutical Industry:
2-Amino-2-(naphthalen-2-yl)ethanol is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Amino-2-(naphthalen-2-yl)ethanol is utilized as a precursor in the creation of novel agrochemicals, enhancing crop protection and yield through targeted pest control.
Used in Organic Synthesis:
2-Amino-2-(naphthalen-2-yl)ethanol is employed as a versatile building block in organic synthesis, facilitating the construction of complex organic molecules with potential applications in materials science and specialty chemicals.
Used in Asymmetric Synthesis:
As a crucial component in the production of chiral ligands and catalysts, 2-Amino-2-(naphthalen-2-yl)ethanol is used to enable enantioselective reactions, leading to the creation of enantiomerically pure compounds essential in various industries.
Used in Therapeutic Applications:
2-Amino-2-(naphthalen-2-yl)ethanol is studied for its potential as a therapeutic agent, particularly for the treatment of various diseases and disorders, highlighting its importance in the field of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 153875-87-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,8,7 and 5 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 153875-87:
(8*1)+(7*5)+(6*3)+(5*8)+(4*7)+(3*5)+(2*8)+(1*7)=167
167 % 10 = 7
So 153875-87-7 is a valid CAS Registry Number.
153875-87-7Relevant academic research and scientific papers
Site-Specific C(sp3)–H Aminations of Imidates and Amidines Enabled by Covalently Tethered Distonic Radical Anions
Fang, Yuanding,Fu, Kang,Shi, Lei,Zhao, Rong,Zhou, Jia
, p. 20682 - 20690 (2020/09/07)
The utilization of N-centered radicals to synthesize nitrogen-containing compounds has attracted considerable attention recently, due to their powerful reactivities and the concomitant construction of C?N bonds. However, the generation and control of N-centered radicals remain particularly challenging. We report a tethering strategy using SOMO-HOMO-converted distonic radical anions for the site-specific aminations of imidates and amidines with aid of the non-covalent interaction. This reaction features a remarkably broad substrate scope and also enables the late-stage functionalization of bioactive molecules. Furthermore, the reaction mechanism is thoroughly investigated through kinetic studies, Raman spectroscopy, electron paramagnetic resonance spectroscopy, and density functional theory calculations, revealing that the aminations likely involve direct homolytic cleavage of N?H bonds and subsequently controllable 1,5 or 1,6 hydrogen atom transfer.
An effective and useful synthesis of enantiomerically enriched arylglycinols
Bandini, Marco,Cozzi, Pier Giorgio,Gazzano, Massimo,Umani-Ronchi, Achille
, p. 1937 - 1942 (2007/10/03)
A two-step synthesis of racemic arylglycinols, together with a simple and straightforward methodology for their resolution, is described. This method constitutes a practical means of preparing racemic and optically pure electron-rich or electron-poor subs