153886-69-2

Basic information

• Product Name: 3-METHYL-8-QUINOLINESULFONIC ACID
• Synonyms: 3-METHYL-8-QUINOLINESULFONIC ACID;3-Methylquinoline-8-sulfonic Acid;Argatroban Impurity 30;3-Methyl-8-Quinolinesulfonic Acid(WX682203)
• CAS NO: 153886-69-2
• Molecular Formula: C₁₀H₉NO₃S
• Molecular Weight: 223.25
• Product Categories: Aromatics Compounds;Aromatics;Sulfur & Selenium Compounds
• Mol File: 153886-69-2.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.432±0.06 g/cm3(Predicted)
• PKA: -1.79±0.40(Predicted)
• CAS DataBase Reference: 3-METHYL-8-QUINOLINESULFONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-8-QUINOLINESULFONIC ACID(153886-69-2)
• EPA Substance Registry System: 3-METHYL-8-QUINOLINESULFONIC ACID(153886-69-2)

Safety Data

• Hazardous Substances Data: 153886-69-2(Hazardous Substances Data)

Usage

Uses

3-Methyl-8-quinolinesulfonic Acid (cas# 153886-69-2) is a compound useful in organic synthesis.

Upstream product

• 612-58-8 3-methylquinoline 
• 88-21-1 2-amino-1-benzenesulfonic acid 
• 123-38-6 propionaldehyde 

Downstream Products

• 74863-82-4 8-(chlorosulphonyl)-3-methylquinoline 
• 698354-12-0 (2R,4R)-4-methyl-1-[(2S)-5-[5-methyl-1-(triphenylmethyl)-1H-imidazol-4-yl]-1-oxo-2-[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino-pentyl]-2-piperidinecarboxylic acid ethyl ester 
• 698354-02-8 (2S)-2-[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino-5-[5-methyl-1-(triphenylmethyl)-1H-imidazol-4-yl]-pentanoic acid 1,1-dimethylethyl ester 
• 698354-07-3 (2S)-2-[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino-5-[5-methyl-1-(triphenylmethyl)-1H-imidazol-4-yl]-pentanoic acid 
• 153886-68-1 1,2,3,4-tetrahydro-3-methyl-8-quinolinesulfonic acid 

Relevant articles and documents

Preparation method of 3-methylquinoline-8-sulfonyl chloride

The invention belongs to the field of fine chemical product production, and particularly relates to a preparation method of 3-methylquinoline-8-sulfonyl chloride, and the method comprises the following steps: (1) carrying out catalytic cyclization on 2-aminobenzene sulfonic acid serving as an initial raw material, propionaldehyde and paraformaldehyde in a deep eutectic solvent to obtain 3-methylquinoline-8-sulfonic acid; and (2) carrying out acylating chlorination on the generated 3-methylquinoline-8-sulfonic acid under the action of an organic alkali by using bis (trichloromethyl) carbonate as a chlorinating agent, thereby obtaining the 3-methylquinoline-8-sulfonyl chloride. The method has the advantages of simple operation process, easily available raw material, low cost, no generation of harmful gases in the whole process, meeting of safety and environmental protection requirements, and facilitation of large-scale production.